The Emerging Link Between Autoimmune Disorders and Neuropsychiatric Disease

A Possible Link between Microglial Process Dysfunction and Neuropsychiatric Disorders

Pío del Río Hortega first discovered microglia by histological staining with silver carbonate. He thought that microglia with highly branched fine processes in the healthy brain were quiescent and called these cells as resting microglia. After brain injury, microglia changes their morphology into activated type, which has phagocytic activity at the sites of neuronal damage and inflammation. At ...

Gut Microbiota and Neuropsychiatric Disorders

A neurophysiological insight into the potential link between transcranial magnetic stimulation, thalamocortical dysrhythmia and neuropsychiatric disorders.

Altered neural oscillations and their abnormal synchronization are crucial factors in the pathophysiology of several neuropsychiatric disorders. There is increasing evidence that the perturbation with an abnormal increase of spontaneous thalamocortical neural oscillations lead to a phenomenon termed Thalamocortical dysrhythmia (TCD) which underlies the symptomatology of a variety of neurologica...

Supplemental Information for : Reevaluation of the link between neuropsychiatric disorders and dysregulated adult neurogenesis

Companion to Table 2: Supplementary Table 1. Causative studies: inducible primary or direct change in dentate gyrus (DG) neurogenesis or DG activity as it relates to DG functional output relevant to neuropsychiatric disorders. Table 2 in the main text provides an overview of this topic, while this Supplemental Table 1 provides the detailed explanation of each publication referred to in Table 2....

The Vital Link Between Chronic Disease and Depressive Disorders

INTRODUCTION Chronic diseases have assumed an increasingly important role in public health research and intervention. Without treatment, depressive disorders characteristically assume a chronic course and are expected, by 2020, to be second only to heart disease in the global burden of disease. Thus, understanding the relationship between depressive disorders and chronic disease appears vital t...